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Successful Scientific Engagement Supported by Amplity Insights
Amplity Insights has contributed numerous analyses to-date, including conference-accepted poster presentations, peer-reviewed journal publications and research led studies examining various scientific theses from physician narratives of real-world patient encounters in the U.S. routine care setting.
ONCOLOGY
Understanding treatment patterns, disruptions, and potential limitations of tyrosine kinase inhibitors in ROS1+ non-small cell lung cancer patients
Understanding Reasons for Treatment Disruption of Tyrosine Kinase Inhibitors in NSCLC Patients
Shim, A. 2022. Understanding Treatment Patterns, Disruptions, and Potential Limitations of Tyrosine Kinase Inhibitors in ROS1+ Non-Small Cell Lung Cancer Patients in a Retrospective Review of United States Electronic Medical Transcription Records. Ispor Europe 2022; Vienna, Austria, and virtual.
Healthcare resource utilization of United States ROS1+ non-small cell lung cancer patients treated with tyrosine kinase inhibitors
Healthcare Resource Utilization in NSCLC Patients
Shim, A. 2022. Healthcare Resource Utilization of United States ROS1+ Non-Small Cell Lung Cancer Patients Treated with Tyrosine Kinase Inhibitors: Analysis of Electronic Medical Transcription Records. Ispor Europe 2022; Vienna, Austria, and virtual.
Identify physicians’ documentation of Granulocyte Colony-Stimulating Factor (G-CSF) utilization, with a focus on Filgrastim-sndz
Uptake of the First U.S. Biosimilar: Filgrastim-sndz Utilization Observed in a Medical Transcription Database
Smoyer, K. 2017. Uptake of the First US Biosimilar: Filgrastim-sndz Utilization Observed in a Medical Transcription Database of Patient Ofce Visits. Ispor USA 2017; Boston, MA, USA.
DIABETES
Assess the prevalence of unrecorded hypoglycemia events by utilizing transcription data and NLP to uncover undiagnosed cases
Prevalence of Hypoglycemia in a Medical Transcription Database
Uzoigwe, C. 2020. 'Assessing Prevalence of Hypoglycemia in a Medical Transcription Database', Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13: 2209–2216.
RARE DISEASE
Describe demographic, clinical characteristics, and the use of genetic testing and patient support tools/services among RP patients
Patient Characteristics and Use of Genetic Testing and Support Services in Retinitis Pigmentosa
Hautamaki, E. Frequency And Nature Of Patient-reported Outcome Conversations Between Physicians And Patients With Cystic Fibrosis.
Understand the patient journey, path to diagnosis, symptom profile, treatment rationale and related demographic factors in ultrarare disease
Primary Hyperoxaluria Type 1
Hautamaki, E. Frequency And Nature Of Patient-reported Outcome Conversations Between Physicians And Patients With Cystic Fibrosis.
NEUROLOGY
Examine the Clinical and Humanistic Burden of Patients With Dravet Syndrome and Lennox-Gastaut Syndrome in the United States
Understanding the patient impact of DS/LGS
Treatment Patterns of Patients With Dravet Syndrome and Lennox-Gastaut Syndrome
Understanding treatment patterns and reasons for treatment discontinuation and switching
Evaluate patient characteristics associated with antiepileptic drug discontinuations and switches among patients with epilepsy
Reasons for Treatment Discontinuation and Switch in Patients With Epilepsy
Velez, F. 2015. Reasons for treatment discontinuation and switch in patients with epilepsy: a retrospective observational study in a US population. 67th American Academy of Neurology Annual Meeting; Washington DC, USA.
Better understand patients’ reason(s) for their adherence and non-adherence, and better understand patients’ reason(s) for switching medications
Patient Reported Motivations for Medication Switching and/or Adherence Challenges Among Patients Diagnosed With Multiple Sclerosis
"Smalarz, A. Patient reported motivations for medication switching and/or adherence challenges among patients diagnosed with Multiple Sclerosis."
AUTOIMMUNE
A pilot study of patients with Systemic Lupus Erythematosus (SLE) initiated on Belimumab
Feasibility of Use of Medical Transcription Data for Real World Evidence Generation
Narayanan, S. Feasibility Of Use Of Medical Transcription Data For Real World Evidence Generation In The United States (US): A Pilot Study Of Patients With Systemic Lupus Erythematosus (SLE) Initiated On Belimumab.
Describe the frequency and nature of PRO conversations and the modalities utilized to alleviate disease burden
Patient-Reported Outcomes in Cystic Fibrosis
Hautamaki, E. Frequency And Nature Of Patient-reported Outcome Conversations Between Physicians And Patients With Cystic Fibrosis.
Understand documentation of disease activity and impact, reasons for adherence/non-adherence/switching, and physician treatment recommendations
Evaluation of Disease Activity in Patients Diagnosed With Rheumatoid Arthritis
"Smalarz, A. Evaluation Of Disease Activity In Patients Diagnosed With Rheumatoid Arthritis: How Often And To What Detail Are Assessments Documented?"
PULMONOLOGY
MENTAL HEALTH
Assess trends in genomic testing from 2008 to 2017 and understand treatment changes among patients due to testing
