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Successful Scientific Engagement Supported by Amplity Insights 

Amplity Insights has contributed numerous analyses to-date, including conference-accepted poster presentations, peer-reviewed journal publications and research led studies examining various scientific theses from physician narratives of real-world patient encounters in the U.S. routine care setting. 

Want to learn more about our database methodologies and representativeness?

 ONCOLOGY 

Biomarker Testing and Targeted Therapy Use Among Patients With Non-Small Cell Lung Cancer in the United States

Jardim, M. 2024. Biomarker Testing and Targeted Therapy Use Among Patients With Non-Small Cell Lung Cancer in the United States: An Analysis Using a Physician Notes Real-World Database. ASCO 2024; Chicago, IL, USA.

Characterizing the rates of biomarker testing and subsequent treatment patterns among patients with NSCLC

Shim, A. 2022. Understanding Treatment Patterns, Disruptions, and Potential Limitations of Tyrosine Kinase Inhibitors in ROS1+ Non-Small Cell Lung Cancer Patients in a Retrospective Review of United States Electronic Medical Transcription Records. ISPOR Europe 2022; Vienna, Austria, and virtual.

Understanding Reasons for Treatment Disruption of Tyrosine Kinase Inhibitors in NSCLC Patients 

Shim, A. 2022. Understanding Treatment Patterns, Disruptions, and Potential Limitations of Tyrosine Kinase Inhibitors in ROS1+ Non-Small Cell Lung Cancer Patients in a Retrospective Review of United States Electronic Medical Transcription Records. ISPOR Europe 2022; Vienna, Austria, and virtual.

Understanding treatment patterns, disruptions, and potential limitations of tyrosine kinase inhibitors in ROS1+ non-small cell lung cancer patients 

Shim, A. 2022. Understanding Treatment Patterns, Disruptions, and Potential Limitations of Tyrosine Kinase Inhibitors in ROS1+ Non-Small Cell Lung Cancer Patients in a Retrospective Review of United States Electronic Medical Transcription Records. ISPOR Europe 2022; Vienna, Austria, and virtual.

Healthcare Resource Utilization in NSCLC Patients 

Shim, A. 2022. Healthcare Resource Utilization of United States ROS1+ Non-Small Cell Lung Cancer Patients Treated with Tyrosine Kinase Inhibitors: Analysis of Electronic Medical Transcription Records. ISPOR Europe 2022; Vienna, Austria, and virtual.

Healthcare resource utilization of United States ROS1+ non-small cell lung cancer patients treated with tyrosine kinase inhibitors 

Shim, A. 2022. Healthcare Resource Utilization of United States ROS1+ Non-Small Cell Lung Cancer Patients Treated with Tyrosine Kinase Inhibitors: Analysis of Electronic Medical Transcription Records. ISPOR Europe 2022; Vienna, Austria, and virtual.

Uptake of the First U.S. Biosimilar: Filgrastim-sndz Utilization Observed in a Medical Transcription Database 

Smoyer, K. 2017. Uptake of the First US Biosimilar: Filgrastim-sndz Utilization Observed in a Medical Transcription Database of Patient Ofce Visits. ISPOR USA 2017; Boston, MA, USA.

Identify physicians’ documentation of Granulocyte Colony-Stimulating Factor (G-CSF) utilization, with a focus on Filgrastim-sndz 

Smoyer, K. 2017. Uptake of the First US Biosimilar: Filgrastim-sndz Utilization Observed in a Medical Transcription Database of Patient Ofce Visits. ISPOR USA 2017; Boston, MA, USA.

DIABETES

Prevalence of Hypoglycemia in a Medical Transcription Database 

Uzoigwe, C. 2020. 'Assessing Prevalence of Hypoglycemia in a Medical Transcription Database', Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13: 2209–2216.

Assess the prevalence of unrecorded hypoglycemia events by utilizing transcription data and NLP to uncover undiagnosed cases 

Uzoigwe, C. 2020. 'Assessing Prevalence of Hypoglycemia in a Medical Transcription Database', Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13: 2209–2216.

 RARE DISEASE 

Describe demographic, clinical characteristics, and the use of genetic testing and patient support tools/services among RP patients 

Patient Characteristics and Use of Genetic Testing and Support Services in Retinitis Pigmentosa 

Hautamaki, E. Frequency And Nature Of Patient-reported Outcome Conversations Between Physicians And Patients With Cystic Fibrosis.

Understand the patient journey, path to diagnosis, symptom profile, treatment rationale and related demographic factors in ultrarare disease 

Primary Hyperoxaluria Type 1 

Hautamaki, E. Frequency And Nature Of Patient-reported Outcome Conversations Between Physicians And Patients With Cystic Fibrosis.

Identification of Generalized Myasthenia Gravis and Antibody Status Using Rules-Based Natural Language Processing Applied to Neurologist Clinical Notes

Darer, J. 2023. Identification of Generalized Myasthenia Gravis and Antibody Status Using Rules-Based Natural Language Processing Applied to Neurologist Clinical Notes. MGFA, AANEM 2023; Phoenix, AZ, USA.

To assess the feasibility of identifying meaningful MG clinical subtypes from neurologist clinical progress notes

Darer, J. 2023. Identification of Generalized Myasthenia Gravis and Antibody Status Using Rules-Based Natural Language Processing Applied to Neurologist Clinical Notes. MGFA, AANEM 2023; Phoenix, AZ, USA.

Real-world Characterization of Challenges Related to the Identification and Management of Myasthenia Gravis Crisis

Darer, J. 2023. Real-world Characterization of Challenges Related to the Identification and Management of Myasthenia Gravis Crisis. MGFA, AANEM 2023; Phoenix, AZ, USA.

To characterize the identification, clinical presentation, and management challenges related to individuals with MG crisis based upon chart review of neurologist clinical progress notes

Darer, J. 2023. Real-world Characterization of Challenges Related to the Identification and Management of Myasthenia Gravis Crisis. MGFA, AANEM 2023; Phoenix, AZ, USA.

Identification of Myasthenia Gravis Exacerbations, Crises, and Symptom Burden Using Rules-Based Natural Language Processing Applied to Neurologist Clinical Notes

Darer, J. 2023. Identification of Myasthenia Gravis Exacerbations, Crises, and Symptom Burden Using Rules-Based Natural Language Processing Applied to Neurologist Clinical Notes. MGFA, AANEM 2023; Phoenix, AZ, USA.

To assess the feasibility of identifying symptoms and clinical deterioration for individuals with MG as documented in neurologist clinical progress notes

Darer, J. 2023. Identification of Myasthenia Gravis Exacerbations, Crises, and Symptom Burden Using Rules-Based Natural Language Processing Applied to Neurologist Clinical Notes. MGFA, AANEM 2023; Phoenix, AZ, USA.

NEUROLOGY

Clinical and Humanistic Burden Associated With Alzheimer’s Disease in the United States

Iwanyckyj, D. 2024. Clinical and Humanistic Burden Associated With Alzheimer’s Disease in the United States: An Analysis of Patient Characteristics, Treatment Patterns, and Quality of Life Using a Physician Notes Real-World Database. ISPOR 2024; Atlanta, GA, USA.

Identification of barriers to patients accessing biomarker evaluation in AD and opportunities to improve the quality of care in different patient populations

Rao, S. 2023. Analysis of Physician Notes to Examine the Clinical and Humanistic Burden of Patients With Dravet Syndrome and Lennox-Gastaut Syndrome in the United States. American Epilepsy Society (AES) 2023; Orlando, Fl, USA.

Examine the Clinical and Humanistic Burden of Patients With Dravet Syndrome and Lennox-Gastaut Syndrome in the United States 

Rao, S. 2023. Analysis of Physician Notes to Examine the Clinical and Humanistic Burden of Patients With Dravet Syndrome and Lennox-Gastaut Syndrome in the United States. American Epilepsy Society (AES) 2023; Orlando, Fl, USA.

Understanding the patient impact of DS/LGS

Rao, S. 2023. Analysis of Physician Notes to Examine the Clinical and Humanistic Burden of Patients With Dravet Syndrome and Lennox-Gastaut Syndrome in the United States. American Epilepsy Society (AES) 2023; Orlando, Fl, USA.

Treatment Patterns of Patients With Dravet Syndrome and Lennox-Gastaut Syndrome

Lu, M. 2023. Antiseizure Medication Treatment Patterns, Reasons for Disruption, and Side Effects for Patients With Dravet Syndrome or Lennox-Gastaut Syndrome: A Retrospective Analysis of US Physician Notes. American Epilepsy Society (AES) 2023; Orlando, Fl, USA.

Understanding treatment patterns and reasons for treatment discontinuation and switching

Lu, M. 2023. Antiseizure Medication Treatment Patterns, Reasons for Disruption, and Side Effects for Patients With Dravet Syndrome or Lennox-Gastaut Syndrome: A Retrospective Analysis of US Physician Notes. American Epilepsy Society (AES) 2023; Orlando, Fl, USA.

Patient Reported Motivations for Medication Switching and/or Adherence Challenges Among Patients Diagnosed With Multiple Sclerosis

Smalarz, A. Patient reported motivations for medication switching and/or adherence challenges among patients diagnosed with Multiple Sclerosis.

Better understand patients’ reason(s) for their adherence and non-adherence, and better understand patients’ reason(s) for switching medications

Smalarz, A. Patient reported motivations for medication switching and/or adherence challenges among patients diagnosed with Multiple Sclerosis.

Reasons for Treatment Discontinuation and Switch in Patients With Epilepsy

Velez, F. 2015. Reasons for treatment discontinuation and switch in patients with epilepsy: a retrospective observational study in a US population. 67th American Academy of Neurology Annual Meeting; Washington DC, USA.

Evaluate patient characteristics associated with antiepileptic drug discontinuations and switches among patients with epilepsy

Velez, F. 2015. Reasons for treatment discontinuation and switch in patients with epilepsy: a retrospective observational study in a US population. 67th American Academy of Neurology Annual Meeting; Washington DC, USA.

Patient Characteristics and Treatment Patterns in Patients With Chronic Migraine

Understand the patient journey, path to diagnosis, symptom profile, treatment rationale and related demographic factors in ultrarare disease

AUTOIMMUNE

Feasibility of Use of Medical Transcription Data for Real World Evidence Generation

Narayanan, S. Feasibility Of Use Of Medical Transcription Data For Real World Evidence Generation In The United States (US): A Pilot Study Of Patients With Systemic Lupus Erythematosus (SLE) Initiated On Belimumab.

A pilot study of patients with Systemic Lupus Erythematosus (SLE) initiated on Belimumab

Narayanan, S. Feasibility Of Use Of Medical Transcription Data For Real World Evidence Generation In The United States (US): A Pilot Study Of Patients With Systemic Lupus Erythematosus (SLE) Initiated On Belimumab.

Patient-Reported Outcomes in Cystic Fibrosis

Hautamaki, E. Frequency And Nature Of Patient-reported Outcome Conversations Between Physicians And Patients With Cystic Fibrosis.

Describe the frequency and nature of PRO conversations and the modalities utilized to alleviate disease burden

Hautamaki, E. Frequency And Nature Of Patient-reported Outcome Conversations Between Physicians And Patients With Cystic Fibrosis.

Evaluation of Disease Activity in Patients Diagnosed With Rheumatoid Arthritis

Smalarz, A. Evaluation Of Disease Activity In Patients Diagnosed With Rheumatoid Arthritis: How Often And To What Detail Are Assessments Documented?

Understand documentation of disease activity and impact, reasons for adherence/non-adherence/switching, and physician treatment recommendations

Smalarz, A. Evaluation Of Disease Activity In Patients Diagnosed With Rheumatoid Arthritis: How Often And To What Detail Are Assessments Documented?

PULMONOLOGY

Physician Behavior Related to Patients Who Present With Uncontrolled Asthma

Assessing HCP actions when treating patients with uncontrolled moderate-to-severe asthma

MENTAL HEALTH

Real World Clinicogenomic Evidence Generation for Mental Health Disorders in the United States

Mehta, J. Use Of Medical Transcription Data For Real World Clinicogenomic Evidence Generation For Mental Health Disorders In US.

Assess trends in genomic testing from 2008 to 2017 and understand treatment changes among patients due to testing

Mehta, J. Use Of Medical Transcription Data For Real World Clinicogenomic Evidence Generation For Mental Health Disorders In US.

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